Synthesis and Study of Acetylenic Amines Derivatives Containing Sulfonamido, β-Naphthoxy and Hippurate Groups

Abstract

New derivatives of acetylenic amines containing sulfonamido, β-naphthoxy
and hippurate groups have been synthesized through Mannich reaction which
involved reaction of N-(1,1-dimethylpropargyl) benzene sulfonamide, propargyl-β-
naphthyl ether and propagyl hippurate with paraformaldehyde and secondary amines.
The structures of the synthesized compounds have been elucidated by physical and
spectroscopic methods. Some of the synthesized compounds showed biological
activity as antibacterial agents.