Substituted of Imidazol As Pendent Bioactive Group Through Chains of Polymers

Abstract

In this research the two new bioactive polymers were prepared by modification of
polyvinylpyrrrolidinone (PVP) or polyvinylchloride (PVC) with Imidazol as known
antimicrobial agent. The two prepared polymers P1 and P2 where characterized by
FT-IR, 1H-NMR and UV. spectroscopies. The physical properties were studied, and
intrinsic viscosities were measured .
The controlled release rates for imidazole units were studied in different pH values
at 37 0C. The swelling percentages were calculated, the two new bioactive polymers
could be used a biomaterials in different health applications.