Elevated Levels Of Salivary Sialic Acid In Periodontitis Disease

Abstract

Sugars are found as a free form present only in traces in fasting saliva. Most of the
carbohydrate content of saliva is in bound form. The carbohydrate part of
glycoproteins is readily split off from the proteins by ill defined bacteria. In saliva
liberating reducing sugars.
A total of 50 volunteers suffering from a case studied periodontitis, they were treated
medically, their total sialic acid and lipid associated sialic acid were investigated.
A comparison study was adopted using 50 samples of healthy subjects as controls.
Significant elevated values of total sialic acid (75.43±0.1mg/dl) and lipid associated
sialic acid (45.04±3.15mg/dl) were found in the cases studied compared with normal
levels in controls (TSA= 60.13±5.06mg/dl, and LASA= 20.41±6.05 mg/dl).
A colorimetric determination was applied to follow the determinations.