Synthesis of New 5-Ethyl-5-Phenyl Barbituric Acid Derivatives

Abstract

The reaction of some new Schiff bases (5-ethyl-5-phenyl-1,3-di[N-4-substituted
benzilidin hydrazinyl] barbituric acids) with benzoyl chloride or 3,5-dinitrobenzoyl
chloride were carried out. Subsequent reactions of these products di[N-(α-
chloro(substituted benzyl)-N-benzoyl or 3,5-dinitro benzoyl)-5-ethyl-5-phenyl-1,3-di(acetic
acid hydrazinyl) barbituric acids with thiourea afforded thioureas compounds.
The synthesized compounds were confirmed by their IR, UV spectra and C.H.N.
analyses data.