spectroscopic study of the effects of permethrin and tetramethrin on some components of the respiratory chain (Coenzyme (10) and Cytochrome C) Qassem Hassan Kazem Falah Sharif Eid Suhail, Faculty of Pharmacy, University of Kufa College of Science / Un

Abstract

The electronic absorption spectroscopy studies the physical properties of pyrethriods in
several solvents with different polarity ( methanol and hexane ) . The maximum wavelength
(λmax) for these compounds have been determined and found to be (221,220) nm for permethrin
and tetramethrin respectively in hexane solvent.
The ultraviolet spectrum proved that there is an interaction ,for the pyrethroid compounds
with electron carriers as part of the respiratory chain components, which have indicated the
formation of complexes through the displacement of the maximum absorption wavelength for
the semi-Coenzyme Q(10) (ubiquinon 0) Ub0 λ=264 nm to (273,272)nm for (per.+ Ub0) and
(Tet. + Ub0) complexes. Also through uv. spectrum, it was approved that there was interactions
occurred between the pyrethroide compounds with electron carrier ( cytochrome C) and the
decrease of molar absorption coefficient, ε values for the mixture components that equal to
(10880 , 5140) l. mol-1. cm-1 for two complexes (cyt.C + per.) , (cyt.C+ Tet.) respectively ,with
(1:1) ratio interactions between mixture components, that equal to (10162) l. mol-1. cm-1 for
cytochrome C alone.
That have certainty occurred and to the formation of complexes with inhibition the respiratory
process with cutting pass of electron and the energy production.