Serum Copper, Zinc, and Magnesium in Toxoplasma-Seropositive Women with a History of Abortion

Abstract

Toxoplasmosis has a high prevalence rate of infection in different countries of
the Arab world including Iraq. Trace elements such as copper (Cu), zinc (Zn), and
magnesium (Mg) have an important chemical and biological roles and may changed in
different diseases. The aim of this work is to study the correlation of the mode of
changes in serum Cu, Zn, and Mg concentrations and the infection by Toxoplasma
gonadii in (IFAT) seropositive women.
Two hundred Iraqi women who have frequent abortion and their sera are
positive in toxoplasmosis test (IFAT) in addition to 100 women for controls (who have
no abortion) were participated in this study. Serum Cu, Zn, and Mg were determined by
the atomic absorption spectrophotometry.
The results of this study revealed that serum copper was markedly elevated
(p<0.05) and serum zinc was significant decreased (p<0.05) in Toxoplasmosisseropositive
women as compared with control. While there is no significant difference
in serum magnesium in the patients group as compared with control.
There are different modes of changes in the serum level of Cu, Zn, and Mg in
patients as compared with normal controls and these modes are explained according to
the immunity response.