Monitoring Some Biochemical Parameters in Serum of Pregnant Women

Abstract

This research includes a comparison between some important biochemical changes in the
pregnant women during different periods of pregnancy. Blood samples were collected from (60)
pregnants and (30) non pregnant women (control group, G3) from different department of Al-
Diwaniyah hospital. The pregnant women were divided into two groups according to the
trimester of pregnancy, G1 (the first twelve weeks) and G2 (twenty eight weeks). Serum was
analyzed for alkaline phosphatase (ALP), Creatine kinase (CK) and Albumin. The results
showed non significant differences (P > 0.05) in serum ALP activity between pregnant women
during first trimester (8.8+2.7 K.A.U/100ml) and the controls (9.3+3.8 K.A.U/ 100 ml). On the
other hand the pregnant women during third trimester (20.8 + 2.8 k.A.U/100ml) showed a
significant raising in ALP activity (P<0.05) when compared to the other two groups. It was also
found that serum creatine kinase activity had a normal value and did not differ among three
groups. Albumin levels were lower in the pregnant women during third trimester (2.78 + 0.33
gm /dL) than in the control group (3.5 + 0.24 gm/ dL) (P<0.05), but the concentration of albumin
in the pregnant women during first trimester (3.05 + 0.3gm/dL) were similar to that of control
group.