Synthesis of Some Diazole, Triazole and Tetrazole Compounds via Imide Intermediate

Abstract

Some open chain compounds (5,6) and pyrazole (12,16) imidazole, triazole
(7,9) and tetrazole (4) compounds were synthesized using phthalimide glycine
derivatives as starting materials, they were converted into substituted acetamide or
acetimidoyl chloride derivatives which were cyclized into the coresponding
heterocyclic compounds using either alcoholic potassium hydroxide or phosphorous
chloride and phenacyl bromide respectively. The final compounds were characterized
using their melting points and the infrared spectroscopy.