The Key Role Correlation Of Creatine Kinase Activity and Antioxidants Status in Diabetic Patients Type I and II

Abstract

The activity of creatine Kinase (CK) estimated, in sera of diabetic patients (36
males, 18 females) type I & II and the concentration of antioxidant variables such as
Glutathione, uric acid compared with healthy controls has been also estimated, CK
activity was found to be significantly decrease in patients with Diabetes Mellitus; while
isoenzyme (MM-CK,BB-CK and MB-CK) levels fluctuated between decrease and
relatively constant in patients with Diabetes mellitus .
Glutathione, uric acid was found to be reduced when compared with those of healthy
controls. The depletion in antioxidant concentrations may be due to their protective
role against oxidative stress in those patients.