Assessments of C-Reactive Protein and its Correlation with Total Antioxidant Capacity in Woman with Poly Cystic Ovary Syndrome

Abstract

Objective: Polycystic ovary syndrome (PCOS) is a common gynecologic endocrinopathy. The pathogenesis of PCOS is associated with both heredity and environment. PCOS has adverse impacts on female endocrine, reproduction, and metabolism. PCOS can impact women’s reproductive health, leading to anovulatory infertility and higher rate of early pregnancy loss. PCOS has additional metabolic derangements, such as insulin resistance, impaired glucose tolerance, and dyslipidemia. The risks of diabetes, cardiovascular disease, hypertension, metabolic syndrome, and endometrial cancer among PCOS patients are significantly increased as well. C-reactive protein (CRP) is a member of a group of acute phase of protein which increase their concentrations during certain inflammation disorders and used as a biomarker of inflammation in the body. The aim of the presented work is to determine the level of CRP and then to evaluate its correlation with total antioxidant capacity in sera of women with PCOS.
Polycystic ovary syndrome, Total antioxidant capacity, Homocystiene , C-reactive protien