Spectral method to estimate the drug alpha-methyldopa in pharmaceutical

Authors

  • Raghida Ismail Waakei

Abstract

Extraction of the drug α_methyldopa from Aldomat ( anti hyper tensive) with hot
water was studied. Reaction of α_methyldopa with Cu+2 was also studied and formed a
complex {Cu-aldomat }The new analytical method based on measurement the molecular
absorbance in UV-Visible spectrum at e max at 780 nm. Optimum pH and divalent copper
ion concentration was estimated. Linearity(0.5-8.5%), detection limit 0.99%, relative
standard deviation %RSD (3.8%) were determined. The complex s identified by UVVisible
and IR spectra . The mole ratio also investigated and found 1:2 ( Cu+2 : aldomat).

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Published

2023-08-05