Synthesis and Characterization some of Pyridine Derivatives

Abstract

Starting compound (2,6-dimethyl-4-phenyl-3,5-diethoxy carbonyl -1,4-
dihydropyridine)(1) has been prepared by treating (2mole) from ethylacetoacetate
with benzaldehyde, which reacted with (2mole) hydrazine hydrate and ethanol to give
hydrazide derivative(2), then converted hydrazide group to oxadiazole and triazole
rings by reacted with (2mole) from carbon disulphide and potassium hydroxide to
give compound(3) and with (2mole) from carbon disulphide and potassium hydroxide
then (2mole) from hydrazine hydrate to give compound (4). hydrazide derivative (2)
also reacted with P-nitrobenzaldehyde and P-chlorobenzaldehyde to give (5) and (6)
respectively.