Relationship between Lipid Profile and Renal Function Parameters in Patients with Acute Myocardial Infarction

Abstract

Background: Cardiovascular disease(CVD) are related to multiple metabolic risk
factor as hypertension , diabetes mellitus, hyperlipidaemia and cystiene level, as well.
Objective: To investigate the association between lipid profile as risk index for CVD
and renal function parameters in patients with acute myocardial infarction (AMI).
Methods: One hundred and one patients (51 males, 50 females) with AMI admitted to
Merjan Teaching Hospital in Hilla city on 2007 and fifty five (30 males, 25 females)
apparently healthy persons as a controls subject to present study. Determination of
blood Total cholesterol (TC), triacylglycerol (TG), high density lipoprotein (HDL)-
cholesterol, serum creatinine (Cr) and serum uric acid (UA) were preformed using
colorimetric methods. Very low density lipoprotein (VLDL)-cholesterol and low
density lipoprotein (LDL) -cholesterol was determined using mathematical method.
Risk index of lipid profile determined by dividing TC/ LDL –cholesterol.
Results: Serum Cr and UA found to be significantly increased in patients with AMI
when compared with healthy controls. Total cholesterol , VLDL- cholesterol, LDLcholesterol
and TG of patient with AMI in both gander found to be significantly
increase when compared with healthy controls. HDL- cholesterol of patients found to
be decreased.
Conclusion: Serum Cr and serum UA can be regarded as risk factor for patient with
CVD.