Environmental Benign Synthesis, Characterization and Antimicrobial Activity of Some Imidazole Derivatives

الملخص

A series of imidazole derivatives by condensation of, differently substituted 4-benzylidene-2-
phenyloxazol-5(4H)-one and 2-aminothiazole, which on further reaction with Urea and Thiourea
produces the final products(substituted 8-phenyl-9-(thiazol-2-yl)-6,9-dihydro-1H-purin-2(3H)-
one 3(a-f) and substituted 8-phenyl-9-(thiazol-2-yl)-6,9-dihydro-1H-purine-2(3H)-thione 4(a-f)).
IR, H1 NMR and MASS spectral data confirmed the structure of the newly synthesized
compounds. All the reactions were carried out by environmental benign, efficient and extremely
fast procedure Microwave synthesis. The derivatives of these moieties were evaluated for
antimicrobial activity.