Preparation , Idendetification and study of The biological activity of Co(II),Ni(II) and Cu(II) with the New Ligand1-[(4-Antipyril)azo]-2- naphthol (4-AAP-2-N)

الملخص

The New ligand of azo naphthol 1-[(4-Antipyril)azo]-2- naphthol (4-AAP-2-N)
have been prepared . Three chelate complexes Have also been prepared by reacting this
ligand with the metal ions Co (II),Ni(II) and Cu(II). The preparation has been conducted
after fixing the optimum conditions of concentration.U.V- visible spectra of these
complexes solutions have been studied for a range of pH and concentrations which obey
Lampert-Beers Law .The structures of complexes are deduced according to mole ratio
method which were obtained from the spectroscopic studies of the complex solutions
.The ratios of metal: ligand obtained are (1:2) for all complexes ions .(UV-Vis)
absorption spectra of ethanolic solution of complexes showed bathchromic shift , as
compared with that of free ligand .The infrared spectra of the chelating complexes have
been studied ,this may indicate that coordination between the metal ions and the prepered
ligand takes place .The conductivity measurements , Elemental analysis ,the percentage
of metal ions and the measurements of magnetic susceptibility of the complexes were
determined ,depending on these results , in addition to, the proposed geometrical
structures of the complexes of Co (II), Ni(II), Cu(II) ions are octahedral . finally the study
of the biological activity of some of these prepared compounds towards two kinds of
disease bacteria, which is a positive bacteria for Gram pigment:
1- Staphylococcus aureus
Second classification for negative bacteria including:
2- pseudomonas aeruginosa
The results showed that some of the prepared compounds had inhibition activity toword
some types of bacteria.