The Correlation between Lactate Dehydrogenase, Creatine Kinase and Total thiol Levels in Sera of Patients with β-Thalassemia

الملخص

Lactate dehydrogenase (LDH), creatine kinase (CK) activities and total thiol levels had
been measured in serum samples for 30 β-Thalassemia patients, aged 7-35 years who had
been treated at Thalassemia center in the Babylon Maternity and children Hospital for the
period between April 2008 to July 2008, compared with 30 healthy controls aged 7-35 years.
The purpose of this study was to investigate the activity of these enzymes and the levels of
total thiol in β-Thalassemia patients as indicators of the relationship between these
parameters and complication of Thalassemia. There was a significant increase of LDH, no
significant decrease of CK activity. There was no statistical significant difference between
patients and controls as regards to total thiol levels.