Synthesis and Characterization and Biological Activity of some New Mannich Basesand Their Metal Complexes with (Cd2+,Ni2+and Mn2+).

Abstract

In this work , five new compounds of mannich bases were synthesized by the
reaction between diketone compounds and ammonia or amine derivatives to give
enamino ketone as intermediate , which may react with aldehydes to yiled
compounds [1-5] ,and complexes[6-8], mannich base[5] reacts with transition metal
ions(Cd+2,Ni+2 and Mn+2) ,to form complexes of the type [6-8].
The synthesized compounds[1-8] are characterized by{(C.H.N)–analysis ,1HNMR-
spectra , FT.IR-spectra} ,stochiometric study, molar conductance ,melting
points,biological study. The data obtained gave good support for synthesized
compounds [1-8] .