Synthesis of Histidine- Amoxillin Condensed Drug Polymer

Abstract

A novel drug polymer as a peptid-biopolymer was prepared from
histidineacidchloride with amoxillinacidchloride, the condensed polymer was
prepared with molar ratio 1:1, this biocompatible, biodegradable, reabsorb able
condensed polymers with controlled lifetimes, which can be used as drug carrier
polymer. The physical properties were measured and the intrinsic viscosity was
measured using Ostwald viscometer, The controlled release rates were studied in
different pH values at 37 0C . The condensed polymer was characterized by UV-vis.
FTIR and 1H-NMR spectroscopy, This biomaterial polymer can be used as non-toxic
substance. When it undergo hydrolytic degradation.