Reaction of D-glycals derivatives with Carbohydrate azides derivatives Via 1,3- dipolarcycloaddition reaction

Abstract

The compounds of the present study are synthesized of disaccharides where
the link between the two carbohydrate groups via a 1,2,3,-triazole or triazoline groups one
type of sugars is unsaturated sugar which contained carbon carbon double bond inside the
ring , like 3,4,6 – tri acetyl glucal and 1,3,4,6,-tetra benzoyl fructal.Addition of seven
azido sugars derivatives to seven tri-O-acetyl-D-glucal and 1,3,4,6,-tetra benzoyl fructal
and their derivatives, by applied 1,3-dipolarcycloaddition reaction seven
Triazolylsaccharides were obtained .The structures of all the products obtained have been
identified by spectral (IR , H1 – NMR ) , elemental( C,H,N) analyses and by some
physical properties .These compounds are expected to show an importance in organic
synthesis and expected to be more stable to enzymatic and chemical hydrolysis . They
may find utility as enzyme inhibitor agents and potentially as pharmaceuticals.