Synthesis and antibacterial study of new thiadiaza-crown ethers on mannose based glycolipid and its analogues.

Abstract

Two new thiadiaza- and triaza-crown ethers on n-dodecyl mannopyranoside have been synthesized and characterized by proton, carbon NMR, high resolution mass spectrometry CHN analysis and FTIR. The antibacterial activities of synthesized macrocycles and their analogues was performed against two gram-negative and two gram-positive bacteria in two cultural media.