Determination of the Concentration Level of Homocystiene in The Serum of Patients With Myocardial and Type II Diabetes in Salahaddin Province

Abstract

Clinical studies predict an increase in the mortality rate among patients with heart disease and diabetes in the world by 2020 because of the symptoms of high blood pressure that leads to aggravation of the cardiovascular disease. Any rise in the level of amino acid in the blood directly contributes to high blood pressure and symptoms of diabetes that are considered a significant exacerbation of the causes of cardiovascular disease. Controversy still holds about the direct and indirect relationship between amino acids and cardiovascular disease (heart attack) and type II diabetes. Therefore, our study included verification of the relationship between amino acid concentration and the symptoms of heart attacks and diabetes type II.
Our research was based on a study of 50 cases of patients of both sexes who suffer from heart disease and Type II diabetes, in addition to 25 healthy persons of 25-45 years of age as a group control. Cases were randomly adopted from outpatient clinics in Tikrit Teaching Hospital. Reliable measurements of amino acid levels in the blood serum of people with stroke, heart attack and diabetes were done by using Eliza technique. They were compared with the approved standard controls. A sharp increase in the concentrations of homocysteine, triglycerides and cholesterol has been observed at the level of statistical significance (p ˂ 0.01) in patients who suffer from stroke, heart disease and diabetes type II compared with the healthy group. Whereas, a different relationship has been observed with folic acid and vitamin B12. The concentration of folic acid at the level of statistical significance (p ˂ 0.01) and the concentration of vitamin B12 at the level of statistical significance (p ˂ 0.05) have decreased in patients with stroke, heart disease, diabetes type II compared with the healthy group.