Adsorption Study of Drug Cefixime onto Surface Iraqi Attapulgite

Abstract

In this study the adsorption of cefixime on Iraqi clay attapulgite. Quantitative estimation of the drug adsorption has been done by utilizing the technique of UV-Vis spectrophotometry at (λmax = 273 nm) at different conditions of temperatures (25, 37 and 45˚C). It was found that, the adsorption decrease with increase the temperature. Study effect of pH (3, 5, 7 and 9) on adsorption of drug on attapulgite and it was found that, the optimum adsorption was achieved at (pH = 3). Study of clay weight of attapulgite in the range of (0.1-1.5 g.) and it was found that, the adsorption increase with increase of clay weight. Finally effect of ionic strength on adsorption process was investigated using a range of NaCl solution (0.1-0.3 M) and it was found that, there was a decrease in adsorption efficiency over attapulgite with increase of ionic strength. The results of adsorption isotherms that were obtained in this study were fitted with Langmuir adsorption isotherm.