Preparation of novel Schiff base complexes of some transition metal (II) derived from 4,-4-ethylenedianiline and antibacterial assessment

Abstract

A particular number of complexes, which include Pd (II), Mn (II), Zn (II), and Ag (I) ions, established from the Schiff base ligand 4,-4-(ethane-1,2-diyl)bis(N-(pyridin-2-ylmethylene)aniline) (C26H22N4) as a 1:1 Molar ratio, were synthesized. We prepared the Schiff base by condensing 4,-4-ethylendianiline and pyridine-2-carboxaldehyde. and characterized the Schiff base ligand and metal complexes using elemental analysis, melting point determination, molar conductance measurement, FT-IR spectroscopy, 1HNMR spectroscopy, powder X-ray diffraction, and biological effectiveness evaluation from the infrared spectrum, electronic spectra, and 1HNMR data. The analysis revealed that the Schiff base ligand donates the electrons of nitrogen (N) atoms to the metal ions. The suggested general formula for the obtained complexes is [M(L)] Cln for Pd (II) and Ag (I) metal ions n can be either 1 or 2. and The formul
[M(L) (H2O)2] OAc2 for Mn(II) and Zn(II) metal ions (L) is a Schiff base ligand with the chemical formula C26H22N4. The proposal suggests the existence of a four-coordinated square planar geometry for the Pd(II) and Ag(I) complexes and a six-coordinated octahedral geometry for the Mn(II) and Zn(II) complexes. The molar conductance measurements of all the complexes indicated their electrolytic character. The silver complex has a conductivity as 1:1 ratio and 2:1 for other complexes. In a laboratory setting, we assessed the antibacterial properties of the Schiff base ligand and its metal complexes against Gram-positive bacteria (Staphylococcus typhi) and Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa) using the Agar disc diffusion method. The antibacterial testing findings demonstrated that the metal complexes displayed a higher level of antibacterial efficacy compared to the unbound Schiff base ligand.